China Corona Virus Outbreak

[kagalingan]

Goodnews to all vaccinated!!! Malas si kags.

ka-noel of cebu, pastillan sounds like pastillas!!!!

Ako pa ba malas ngayon sa nangyayari sa inyo vaccinated, over disinfectant, chugging lots of ascorbic acid, using uv as eyemo hahaha.

Pinaglalaruan na nga kayo at ang bago eh from sputnik ano daw next astra dahil viral vector. Ginagawa kayo sawsawan.

Kags lang sinuswerte dito sa tsikot

[uls]

monoclonal antibodies developed to fight covid can't neutralize delta

(mAbs are antibodies in vials)



look at the 2nd and 4th mAb

remember what they gave Trump when he had covid?

Regeneron



Regeneron is made up of 2 mAbs

REGEN-COV (casirivimab and imdevimab) FDA Approval Status - Drugs.com

REGEN-COV is a combination of two monoclonal antibodies (casirivimab and imdevimab) designed specifically to block the infectivity of SARS-CoV-2, the virus that causes COVID-19.

it's unlikely to be effective against delta

[Monseratto]

FDA poised to OK third COVID-19 vaccine dose for immune-compromised people

The Food and Drug Administration is poised to amend the emergency use authorizations for the Pfizer and Moderna COVID-19 vaccines Thursday to allow people with compromised immune systems to get a third dose, according to two sources familiar with the plans.

Doctors say it is increasingly clear that many such patients are still vulnerable to COVID-19 following vaccination because they may not mount an effective immune response to the shots.

An estimated 2.7% of adults in the United States are immune-compromised, according to the CDC. It is unclear which groups would be covered under the expected FDA action. Immune-compromised patients include organ transplant recipients, people undergoing cancer treatment and people with HIV, among others.

[kagalingan]

tsikoteers,

Tanggapin nyo na taon-taon kayo tuturukan. Panindigan nyo aral kayo sa top school. LET YOUR CHILDREN TAKE THE VACCINE. hahahaha!!!!!

[Monseratto]

Sinovac's booster shot vs Delta?

INOVIO and Advaccine Receive Regulatory Allowance for Two Heterologous Prime-Boost Clinical Trials in China Using INO-4800, INOVIO's COVID-19 DNA Vaccine Candidate

INOVIO (NASDAQ:INO), a biotechnology company focused on bringing to market precisely designed DNA medicines to treat and protect people from infectious diseases, cancer, and HPV-associated diseases, today announced that it has received regulatory allowance for two clinical trials investigating heterologous boosting with INO-4800, its DNA vaccine candidate for COVID-19, through partner and trial-sponsor Advaccine Biopharmaceuticals Suzhou Co., Ltd. ("Advaccine") together with Sinovac Biotechnology ("Sinovac"). The studies will evaluate the safety, tolerability and immunogenicity of heterologous prime-boost sequential immunizations using INO-4800 and CoronaVac®, an inactivated COVID-19 vaccine developed by Sinovac and validated by the World Health Organization (WHO) for emergency use.

China's Center for Drug Evaluation of the National Medical Products Administration has allowed the initiation of two Advaccine-sponsored open-label, positive-control trials to evaluate the safety, tolerability, and immunogenicity of mixed boosted regimens. Both studies, which will be conducted in China, are anticipated to begin this fall and will involve healthy adult subjects 18 years of age or older.

The companies completed cross prime-boost pre-clinical animal tests using INO-4800 and CoronaVac®, demonstrating that the prime-boost strategy can stimulate high-level of antigen specific binding antibodies, neutralizing antibodies by both live-virus neutralization assay and hACE2 receptor blocking assay, and antigen-specific T cell immune responses.


Recent analysis using clinical samples showed that INO-4800 maintained a robust T cell level against the delta variant, when compared to T-cell responses from the original wildtype strain, further demonstrating INO-4800's ability to generate CD8 T cells, which INOVIO believes will be crucial in mitigating against rising variants such as delta. This data complements the Phase 1 and 2 trial data for INO-4800, which highlighted key advantages across INOVIO's DNA medicines platform – specifically, the ability to induce a balanced immune response that includes engagement of both T cells and B cells.

In parallel with INO-4800, INOVIO is also developing a novel, pan-COVID, second-generation vaccine candidate, INO-4802, which is designed to protect against current and future variants of concern. In May 2021, INOVIO published a manuscript in BioRxiv that demonstrated cross-reactive immune responses against current and emerging viral variants using INO-4802 as either a first-line vaccine or potentially as a booster for individuals previously immunized with various wildtype strain-matched vaccines. Specifically, INO-4802 induced potent neutralizing antibodies and T cell responses against the original wildtype strain as well as against alpha, beta, gamma, and delta variants in pre-clinical models.

About INO-4800

INO-4800 is INOVIO's DNA vaccine candidate against SARS-CoV-2, the novel coronavirus that causes COVID-19. INOVIO has extensive experience working with coronaviruses. The company recently dosed its first participant in a Phase 2 trial for INO-4700, its DNA vaccine candidate for the prevention of Middle East Respiratory Syndrome (MERS), a coronavirus that is 100 times deadlier than COVID-19.

Composed of a precisely designed DNA plasmid, INO-4800 is injected intradermally followed by electroporation using a proprietary smart device delivering the DNA plasmid directly into cells in the body and is intended to produce a well-tolerated immune response. INO-4800 is the only nucleic-acid based vaccine that is stable at room temperature for more than a year, at 37o C for more than a month, has a five-year projected shelf life at normal refrigeration temperature and does not need to be frozen during transport or storage – all of which Inovio believes are important considerations for mass immunizations.

[bloowolf]

YouTube suspends Rand Paul for one week over mask effectiveness claims


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[Monseratto]

Meanwhile in da banana republic...

[Athrunzala]

Meanwhile in da banana republic...

Covid fatigue na by next year

[bloowolf]

Kumbaga sa kotse, Hyundai-Kia

FDA allows emergency use of donated UAE-made COVID-19 vaccines


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[Monseratto]

Owner of Manosa

Hi all, there are posts circulating in social medias, saying "Owner of Mañosa/Maki Haus died of Covid". With a heavy heart, I am confirming that this unfortunate incident indeed took place yesterday. My cousin Terrence Chan, 41 years old, only son of my maternal uncle, passed away yesterday afternoon at home. He was confirmed to be Covid positive on Aug 7, diagnosed to be mild case with minimal symptoms, subjected to home care with 24 hours stay in nurse. From Aug 7 to Aug 10, his condition remained stable and normal, except fever didn't go away, Aug 10 evening, fever shot up to past 40 C. Within less than 20 hours his health condition deteriorated drastically, till 3pm yesterday cardiac arrest ended his life, left his pregnant wife and elderly parents behind...

[Monseratto]

Sa mga ayaw maturukan...

Thailand to start human trials on COVID-19 shots via nasal spray

Two coronavirus vaccines administered using a nasal spray being developed in Thailand are due to start human trials by the end of this year, after promising results in trials involving mice, a government official said on Wednesday.

Developed by the National Center for Genetic Engineering and Biotechnology, the vaccines are based on the adenovirus and influenza, deputy government spokeswoman Ratchada Thanadirek said.

After conducting trials in mice, the first phase of human trials should start by the end of this year, pending approval from the food and drug regulator, she said.

[uls]

Meanwhile in da banana republic...

di pa applicable sa atin yan coz madami pa di pa nababakunahan

sasabihin ng mga tao bakit bibigyan ng 3rd dose ung iba samantala madami pa walang 1st dose

pwede private

i think madami sa mga naghihintay ng novavax nagpabakuna na ng sinovac

so ung dadating na novavax sa Q4 pwede gawin booster

[Athrunzala]

tsikoteers,

Tanggapin nyo na taon-taon kayo tuturukan. Panindigan nyo aral kayo sa top school. LET YOUR CHILDREN TAKE THE VACCINE. hahahaha!!!!!

baket, ano ba latest rumor nakuha mo?

[uls]

^^^

kahit wala rumor... obvious naman papunta doon yun

[shadow]

Eh ano naman kung booster every year parang flu vacc.


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[tsupermario]

Cases of breakthrough infections among the vaccinated remain rare. In that event, health experts said, a fully vaccinated person who gets COVID-19 won’t be contagious for very long and may not have the chance to transmit the virus to another person.

A vaccinated person may have the same viral loads as an unvaccinated person, but that high level of virus lasts only three to four days compared with an unvaccinated person who could be contagious for up to 10 days, said Suresh Mittal, professor of virology at Purdue University’s College of Veterinary Medicine.

“Individuals who are vaccinated have a good immune response. If they get in contact with people who are infected, they might get infected, but the majority may not transmit,” he said.

It's even more uncommon for a vaccinated person to transmit the virus to another vaccinated person, though "not impossible," said Dr. Shaun Truelove, assistant scientist at the Johns Hopkins Bloomberg School of Public Health.

"We think it's quite rare that a vaccinated individual is infecting another vaccinated individual," he said. "At this time, we really don’t have sufficient data to quantify what that risk is, but as this resurgence continues to grow with the delta variant ... the number of individuals who are vaccinated and infected from another vaccinated individual will continue to occur and potentially continue to grow, though likely remaining small and rare."

Nationally, so-called breakthrough infections represent a small fraction of COVID-19 cases. Out of the more than 163 million people in the USA who have been fully vaccinated, about 6,500 patients with a breakthrough infection were hospitalized or died as of July 26, according to the Centers for Disease Control and Prevention.

“While we know that people who are fully vaccinated can get the delta variant and give it to others, our vaccines are still doing an incredible job of keeping us safe,” said Jodie Guest, professor and vice chair of the department of epidemiology at Emory University’s Rollins School of Public Health.

COVID transmission among vaccinated, unvaccinated. What experts say.

[ale828]

Sinovac in Mandaluyong, Moderna in QC: Authorities probe double vaccination scheme | ABS-CBN News

Based on social media posts seen by ABS-CBN News on Thursday, the man got his second dose of Sinovac in Mandaluyong on May 10, and got another virus jab manufactured by Moderna in Quezon City just this week.

Bawal daw yung Booster shots.

Paano naman ma monitor yan at paiba iba yung system ng vaccination card ng ibat ibang municipalities/cities.

[thearsenal1205]

Sa mga ayaw maturukan...

Thailand to start human trials on COVID-19 shots via nasal spray

This is good news for those have a phobia on syringes.

For those have a phobia on vaccines... hmmm..

[_Cathy_]

tsikoteers,

Tanggapin nyo na taon-taon kayo tuturukan. Panindigan nyo aral kayo sa top school. LET YOUR CHILDREN TAKE THE VACCINE. hahahaha!!!!!

ENOUGH TROLLING! You are isolated from the board for the rest of the ECQ. Leave children out of this!

MODERATOR'S NOTE: Kagalingan is banned for 7 days.

[170kphlang]

ENOUGH TROLLING! You are isolated from the board for the rest of the ECQ. Leave children out of this!

MODERATOR'S NOTE: Kagalingan is banned for 7 days.

Kags, must be sad and lonely in real life. Coping and defense mechanism nalang yung pangttroll, ksp, at pabida just to get a small amount of escape and joy from reality. I hope his life is as awesome as he projects it here.

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