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  1. Join Date
    Sep 2012
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    842
    #21581
    The Whole Virus (Inactivated Virus) technology seems more effective at any variants.

    A killed virus vaccine is likely to offer greater protection
    Last edited by TopEngine; March 4th, 2021 at 11:11 AM.

  2. Join Date
    Sep 2003
    Posts
    25,189
    #21582
    Quote Originally Posted by 111prez View Post
    Brazil versus the CHINA WUHAN VIRUS


    Now this: Sao Paulo back on 'code red' as COVID-19 batters Brazil | ABS-CBN News

    "SAO PAULO - Brazil's biggest state, Sao Paulo, declared new "code red" restrictions over COVID-19 Wednesday, ordering non-essential businesses closed for two weeks as an explosion of cases swept the country."

    ""We're going to face the two worst weeks since March last year," said Governor Joao Doria."

    Dito, mukhang Pasay ang bagong SanWuhan ng Pilipinas
    Brazil P.1 new gen variant that is infecting the younger group. Not suprising after Brazll explosive surge was the perfect environment for mutation to thrive.

    The IATF will be sending a junket to INDIA to finalize deal with next gen vaccine that can deal with the UK and SA variants.

    .

    Preliminary analysis indicates that the UK variant strain that was increasingly prevalent was detected in over 50% of the PCR-confirmed symptomatic cases (32 UK variant, 24 non-variant, 6 unknown). Based on PCR performed on strains from 56 of the 62 cases, efficacy by strain was calculated to be 95.6% against the original COVID-19 strain and 85.6% against the UK variant strain [post hoc].

    In the South Africa Phase 2b clinical trial, 60% efficacy (95% CI: 19.9 – 80.1) for the prevention of mild, moderate and severe COVID-19 disease was observed in the 94% of the study population that was HIV-negative. Twenty-nine cases were observed in the placebo group and 15 in the vaccine group. One severe case occurred in the placebo group and all other cases were mild or moderate. The clinical trial also achieved its primary efficacy endpoint in the overall trial population, including HIV-positive and HIV-negative subjects (efficacy of 49.4%; 95% CI: 6.1 – 72.8).
    Galvez off to India to negotiate supply of Novavax vaccines

    The government is eyeing to purchase 30 million doses of Novavax vaccines from SSI, which is expected to start arriving in the country by May, 2021.
    Last edited by Monseratto; March 4th, 2021 at 11:22 AM.

  3. Join Date
    Nov 2005
    Posts
    45,927
    #21583
    Quote Originally Posted by TopEngine View Post
    The Whole Virus (Inactivated Virus) technology seems more effective at any variants.

    A killed virus vaccine is likely to offer greater protection
    yup theory ko din

    Kung ayaw china inactivated vaccine meron india

  4. Join Date
    Oct 2002
    Posts
    40,599
    #21584
    Ang issue ko pa rin sa China vaccines bakit ayaw nila ilabas yun data ng 3rd stage trial nila?

    Tayo ba ang 3rd stage trials?


    Sent from my iPhone using Tapatalk

  5. Join Date
    Oct 2002
    Posts
    21,433
    #21585
    Quote Originally Posted by shadow View Post
    Ang issue ko pa rin sa China vaccines bakit ayaw nila ilabas yun data ng 3rd stage trial nila?

    Tayo ba ang 3rd stage trials?


    Sent from my iPhone using Tapatalk
    Pero marami nang nauna sa atin gumamit ng sinovac and sinopharm. So baka lahat yan is part of their 3rd phase trials?
    Signature

  6. Join Date
    Nov 2005
    Posts
    45,927
    #21586
    Quote Originally Posted by Deestone View Post
    I talk with my colleague yesterday and we were talking about covid virus and he told me that he now believes that the virus might not originate really from wuhan china. Because of may variants right now from other countries but no china wuhan new variant reported.

    Sent from my SM-N910C using Tsikot Forums mobile app
    Sir in order for the virus to mutate kailangan nakababad siya matagal sa loob ng tao

    then para kumalat siya, ung mutant kailangan lumipat sa ibang tao

    sa China kasi they literally shut down entire cities test every person and isolate all positives

    so the virus has less chance to mutate or even if there are mutations, less chance to spread

    kaya mapansin mo kung saan may VOC (variant of concern) sila ung nagkaroon ng large outbreak (UK, Brazil, South Africa, US)

    pati Pinas meron homegrown variant na-identify sa Cebu (remember Cebu had a large outbreak last year)

  7. Join Date
    Nov 2005
    Posts
    45,927
    #21587
    Quote Originally Posted by shadow View Post
    Ang issue ko pa rin sa China vaccines bakit ayaw nila ilabas yun data ng 3rd stage trial nila?

    Tayo ba ang 3rd stage trials?


    Sent from my iPhone using Tapatalk
    tingin ko di na sila nag abala pa

    they don't need to comply with western standards

    they aren't seeking approval of US, UK, EU regulators

    ang market nila developing world

    mas lax ang developing world, mas flexible ang mga gobyerno

    may sariling mundo ang china

    they don't subscribe to the standards, institutions, processes designed by the West

  8. Join Date
    Feb 2008
    Posts
    12,683
    #21588
    Quote Originally Posted by Deestone View Post
    I talk with my colleague yesterday and we were talking about covid virus and he told me that he now believes that the virus might not originate really from wuhan china. Because of may variants right now from other countries but no china wuhan new variant reported.

    Sent from my SM-N910C using Tsikot Forums mobile app
    Precisely why those are being called variants because the origin is Wuhan, China.

  9. Join Date
    Nov 2005
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    45,927
    #21589
    pero eto

    di ba kayo nagtataka bakit walang astrazeneca vaccine sa US?

    bakit hindi nag apply ng EUA ang AZN sa US FDA?

  10. Join Date
    Mar 2008
    Posts
    54,644
    #21590
    Quote Originally Posted by uls View Post
    pero eto

    di ba kayo nagtataka bakit walang astrazeneca vaccine sa US?

    bakit hindi nag apply ng EUA ang AZN sa US FDA?
    sirit!
    (share it!).

  11. Join Date
    Sep 2003
    Posts
    25,189
    #21591
    Quote Originally Posted by shadow View Post
    Ang issue ko pa rin sa China vaccines bakit ayaw nila ilabas yun data ng 3rd stage trial nila?

    Tayo ba ang 3rd stage trials?


    Sent from my iPhone using Tapatalk
    Walang 3rd stage trial sa China... too few cases to conduct one. Kaya they relied on other counties to conduct their third phase trials... SINOVAC used Indonesia and Brazil. Sinopharm sa UAE.

  12. Join Date
    Sep 2003
    Posts
    25,189
    #21592
    Quote Originally Posted by uls View Post
    pero eto

    di ba kayo nagtataka bakit walang astrazeneca vaccine sa US?

    bakit hindi nag apply ng EUA ang AZN sa US FDA?
    Tagal magabas ng 3rd phase trial data... It was also delayed because of severe side effects cases.

    AstraZeneca expects U.S. trial results in next 4-6 weeks, research chief says | Reuters


    One of the U.S. trial investigators, who was not authorised to speak on behalf of the company, said on Friday the trial now had enough data to do an interim analysis, and investigators were cleaning the data so that data safety monitors could start analysing it.

    “We’re all hoping that there will be some data for them to be able to put together a report for the FDA to apply for emergency use authorization by the end of the month (February),” the investigator said.

    AstraZeneca and its partner, Oxford University, say their COVID-19 vaccine, which is already approved for emergency use in about 50 countries, has 76% efficacy against symptomatic infection for three months after a single dose, and that this is increased if the second shot is delayed.

  13. Join Date
    Nov 2005
    Posts
    45,927
    #21593
    scientists have been tracking SARSCOV2 mutations since the start of the pandemic

    remember last year pinagusapan ang mutation from d614 to g614?

    the original virus from China has already been replaced by mutants

    matagal na



    March 2020 pa


  14. Join Date
    Nov 2005
    Posts
    45,927
    #21594
    where do mutants arise?

    in places where there were large outbreaks




    fast forward to 2021

    D614G mutant which is more infectious than the ancestral virus is old news

    now there are mutants that are even more infectious than D614G and are able to escape antibodies of those who were previously infected
    Last edited by uls; March 4th, 2021 at 12:33 PM.

  15. Join Date
    Nov 2005
    Posts
    45,927
    #21595
    so if you got covid last year and you got antibodies na...

    pag nahawaan ka ng variant na may escape mutation, your antibodies will not attach to them

    it will be like experiencing covid for the first time again

    back to zero

  16. Join Date
    Mar 2010
    Posts
    2,275
    #21596
    Quote Originally Posted by uls View Post
    so if you got covid last year and you got antibodies na...

    pag nahawaan ka ng variant na may escape mutation, your antibodies will not attach to them

    it will be like experiencing covid for the first time again

    back to zero
    We are so late at the outset!

    '''When will it end?''': How a changing virus is reshaping scientists’ views on COVID-19 | Reuters

  17. Join Date
    Mar 2006
    Posts
    19,003
    #21597
    paktay na!

    Hong Kong health authorities on Tuesday night revealed that they were investigating the death of a chronically ill man two days after he received China’s Sinovac Covid-19 vaccine, but cautioned that no connection had been ascertained yet.

    Hong Kong authorities looking into death of chronically ill man two days after receiving Sinovac Covid-19 vaccine | South China Morning Post




    South Korean authorities on Wednesday said they are investigating the deaths of two people after a media report said the pair – both with pre-existing conditions – died within days of receiving AstraZeneca’s COVID-19 vaccine.

    South Korea probing two deaths after AstraZeneca's COVID-19 vaccine – KDCA | Inquirer News


    damned if you will, damned if you don't.

  18. Join Date
    Mar 2008
    Posts
    54,644
    #21598
    i pray that covid mutates itself out of our lives.

  19. Join Date
    Nov 2005
    Posts
    45,927
    #21599

  20. Join Date
    Nov 2005
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    45,927
    #21600
    Quote Originally Posted by dr. d View Post
    i pray that covid mutates itself out of our lives.

China Corona Virus Outbreak