China Corona Virus Outbreak

[ale828]

EEEK!!!

https://www.washingtonpost.com/healt...46d_story.html

if the mutation is in the main Spike protein then it might reduce the effectiveness of the MRna vaccines of Pfizer and Moderna since they use the Spike protein as their main ingredient to produce antibodies.
IN Theory should the vaccines that use inactivated covid virus produce a better response since the antibodies they produce will not only be for the spike protein but also to the other parts of the Covid virus?

[uls]

if the mutation is in the main Spike protein then it might reduce the effectiveness of the MRna vaccines of Pfizer and Moderna since they use the Spike protein as their main ingredient to produce antibodies.
IN Theory should the vaccines that use inactivated covid virus produce a better response since the antibodies they produce will not only be for the spike protein but also to the other parts of the Covid virus?

since inactivated whole virus vaccines expose the immune system to the WHOLE virus, the body will produce antibodies that will attach not only to the spike but also to other parts of the virus

i was thinking that for some time but didn't post it here coz masyado anti china dito

coz sinopharm and sinovac are inactivated virus vaccines

[Wh1stl3r]

Variants, 3 New Covid Vaccines, and Contested Efficacy Claims: A Month of Seismic Shifts and Confusion - Absolutely Maybe

[uls]

current vaccines still work on new variants but less effective than on older variants (coz current vaccines were designed based on older variants)

kung more than 90% efficacy on older variants, that can drop to 60% or lower when confronted with new variants

kaya habang effective pa you wanna vaccinate as many people as possible

fight against time ito

[Tha_Mann]

since inactivated whole virus vaccines expose the immune system to the WHOLE virus, the body will produce antibodies that will attach not only to the spike but also to other parts of the virus

i was thinking that for some time but didn't post it here coz masyado anti china dito

coz sinopharm and sinovac are inactivated virus vaccines

I think even before pa, na kung sino man makaka gawa ng better/effective vaccine eh China na yun. for one, sa kanila nanggaling yun and kumbaga eh may head start na sila to create a vaccine.

they are getting a bad rep because of their own doing din naman. kulang sa transparency yung data nila like the details of their trials remain unpublished (or hindi ko pa din nabasa hehe).

very much appreciated yung mga posts mo bro, very informative and no need ko na mag research minsan haha.

[uls]

I think even before pa, na kung sino man makaka gawa ng better/effective vaccine eh China na yun. for one, sa kanila nanggaling yun and kumbaga eh may head start na sila to create a vaccine.

they are getting a bad rep because of their own doing din naman. kulang sa transparency yung data nila like the details of their trials remain unpublished (or hindi ko pa din nabasa hehe).

very much appreciated yung mga posts mo bro, very informative and no need ko na mag research minsan haha.

hehe

but i wouldn't say China intentionally used inactivated virus to make their vaccines coz they think it's better

it's just that yan lang alam nila paraan how to make vaccines... the old fashioned way

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the West leads the world in mRNA research kaya nauna talaga ang West sa mRNA vaccines

[uls]

though meron China company gumagawa ng viral vector vaccine (CanSino Biologics)

some Canada-China relationship kaya CanSino

-

and recently i came across a china company with a mRNA vaccine in phase 1

sigurado may mga tataas ang kilay just reading the words hehe

[uls]

more companies to make mRNA vaccines

mRNA is the hottest thing now in vaccine tech

[Deestone]

more companies to make mRNA vaccines

mRNA is the hottest thing now in vaccine tech

mRNA for youngster and non replicating for adults that is the general rule right.

Sent from my SM-N910C using Tsikot Forums mobile app

[uls]

mRNA for youngster and non replicating for adults that is the general rule right.

Sent from my SM-N910C using Tsikot Forums mobile app

alam ko saan galing yan... kay Dr Richard Mata hehe

[uls]

parang kailan lang sabi ko walang china vaccine sa COVAX

eto kanina lang...

[Deestone]

alam ko saan galing yan... kay Dr Richard Mata hehe

Yes I think so it was before he was comparing mRNA and non replicating it was the incident in norway wherein elderly people died after takinh pfizer shot. But it is incorrect to state that as a general rule? what other doctors are saying about this?

Sent from my SM-N910C using Tsikot Forums mobile app

[Monseratto]

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the West leads the world in mRNA research kaya nauna talaga ang West sa mRNA vaccines

Foundations Advancing mRNA Technology and Science - Moderna

In January 2016, we entered a global health project framework agreement with the Bill & Melinda Gates Foundation to advance mRNA-based development projects for various infectious diseases. The Bill & Melinda Gates Foundation has committed up to $20.0 million in grant funding to support our initial project related to the evaluation of antibody combinations in a preclinical setting as well as the conduct of a first-in-human Phase 1 clinical trial of a potential mRNA medicine to help prevent human immunodeficiency virus, or HIV, infections. Follow-on projects which could bring total potential funding under the framework agreement up to $100.0 million (including the HIV antibody project) to support the development of additional mRNA-based projects for various infectious diseases can be proposed and approved until the sixth anniversary of the framework agreement, subject to the terms of the framework agreement, including our obligation to grant to the Bill &Melinda Gates Foundation certain non-exclusive licenses.

[111prez]

A bit of good news for us on this CHINA WUHAN VIRUS affliction: No COVID-19 spike in NCR due to holidays, Black Nazarene feast —OCTA

[uls]

Deestone i haven't come across other doctors explain the vaccines like Dr Mata did

[uls]

Foundations Advancing mRNA Technology and Science - Moderna

i'm fascinated with the story of Katalin Kariko

she was the one who pursued mRNA research in the 1990s when nobody else was interested

trying reading about her story

[Monseratto]

Di na mapapasa yung veerus at the first dose...

Covid-19 Live Updates: Study Finds AstraZeneca Shots Drastically Cut Transmission - The New York Times

“We now know that the Oxford vaccine also reduces transmission and that will help us all get out of this pandemic,” Mr. Hancock said in an interview Wednesday morning with the BBC.

The results, he said, “should give everyone confidence that this jab works not only to keep you safe but to keep you from passing on the virus to others.”

The Oxford and AstraZeneca researchers also found that a single dose of the vaccine was 76 percent effective at preventing Covid-19. The data measured the three months after the first shot was given, not including an initial three-week period needed for protection to take effect.

[uls]

check this out

GSK and Curevac looking ahead

will make multi-valent covid vaccine (coz mutants)

for pandemic and endemic use (coz they know the virus ain't going away)

2nd gen vaccine

[uls]

Di na mapapasa yung veerus...

Covid-19 Live Updates: Study Finds AstraZeneca Shots Drastically Cut Transmission - The New York Times

mas ok pa yata single dose niyan kesa 2 dose

[Monseratto]

Russki Vaccine as released by Lancet


Russia's Sputnik V vaccine is 91.6% effective against symptomatic Covid-19 - CNN

The Sputnik V vaccine is a two-dose adenoviral vector vaccine using two different adenoviruses for each dose, with doses administered 21 days apart. With this type of vaccine, an adenovirus is altered so that it can deliver a piece of genetic material from the virus that causes Covid-19 into the body and get cells to express the spike induce found on the virus and induce an immune response. It's an approach similar to the vaccines developed by AstraZeneca and Johnson & Johnson.

The authors say that using a different adenovirus vector for the booster vaccination may help create a more powerful immune response.

One advantage of adenoviral vaccines is that they do not need to be stored and transported in extremely cold temperatures, scientists say. Sputnik V only needs to be refrigerated and costs $10 per dose, according to Russian Direct Investment Fund, which funded vaccine production and is responsible for selling it globally.

"This is a useful addition to the published data on Covid-19 vaccine effectiveness," Dr. Julian Tang, clinical virologist at the University of Leicester.

But he highlighted that "median follow up was 48 days from the first dose, so the study cannot assess the full duration of protection."