Baba ng efficacy ng Sinovac... 50% lang. Pero OK na daw yung sabi ng DOST since WHO minimum is 50%. Mediocrity being the hallmark of Public service in da PH...
Sinovac vaccine’s 5 % efficacy is acceptable—DOST | Inquirer News
The second variant from South Africa has reached UK..
Another new variant of COVID-19 virus found in the UK: Health minister - CNA
- - - - - - - - - - - - - - - - - - - - - -"This new variant is highly concerning, because it is yet more transmissible, and it appears to have mutated further than the new variant has been discovered in the UK," he said.
Singapore confirms first case of new coronavirus variant found in UK | ABS-CBN News
evolving new variants is nothing new.
the influenza virus has many types, subtypes, and strains.
what i wish for, is that the subsequent covid variants will prove to be as lethal to ordinary humen as the common cold...
who knows,
the covid 19 virus might eventually disappear into the pages of medical history as an ordinary, self-limiting, non-lethal virus...
Last edited by dr. d; December 24th, 2020 at 06:33 PM.
Sinovac was asking Brazil to withold the results until Indonesia and Turkey releases their respective 3rd phase trials...
But cat is out of the bag.
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50% is internationally acceptable standard.
even the popular flu vaccine is only 40-60% effective...
50% effective is a lot better than 0% effective (aka no vaccine).
yes, i know it smacks of the "puede na" mentality.
but hey! think "herd immunity".
personally,
i think the preference of some markets for pfizer and astra over sinovac, is more of a political decision...
but that's just me.
hey!
these vaccines are not even a year old!
it will take many years, for a decision on which vaccine is the superior one...
Last edited by dr. d; December 24th, 2020 at 09:47 PM.
After UK and SA, now may Nigerian strain...
Another new coronavirus variant appears to emerge in Nigeria, Africa CDC says | South China Morning Post
Wait for a peer to peer paper to get the real efficacy on the Sinovac vaccine...
Coronavirus: Turkey says China’s CoronaVac vaccine 91.25 per cent effective | South China Morning Post
pfizer and moderna's vaccines cause the immune system to make very specific antibodies coz they present only the spike protein to the immune system
sinopharm and sinovac's inactivated virus vaccines present the whole virus to the immune system so antibodies produced are varied (the body makes antibodies to more parts of the virus not only the spike) -- parang antibodies in convalescent plasma
that may explain why pfizer and moderna's vaccines have higher efficacy coz antibodies produced are concentrated
in inactivated virus vaccines many of the antibodies produced aren't very useful and the most useful ones (the ones that bind to the spike) aren't as many
re mutations
changes to the spike can go too far that antibodies (generated by currenct vaccines) don't recognize or only partially recognize
keep in mind all SARSCOV2 vaccines being manufactured now are designed based on older variants of the virus (as old as January 2020 variants)
1 year into the pandemic the virus underwent a lot of evolutionary pressure in human immune systems
our immune systems try to neutralize it, it wants to survive
we use antivirals to eliminate it, it wants to survive
so it's inevitable that variants with higher survival advantage arise and become the dominant variant
Last edited by uls; December 25th, 2020 at 12:31 PM.
there are variants that can escape antibodies in convalescent plasma
antibodies that can hunt down wild type virus can't see new mutants
ang intindi ko sa pfizer and moderna vaccines eh parang instructions lang pinapadala nila sa immune system natin like ito yun itsura ng virus so pag na infect ka alam na nila unlike conventional vaccines na virus talaga mismo pinapadala,
re:inoculation
papayagan ba private mag pasok ng sariling vaccine or kailagan dumaan lahat sa govt? I mean do we have a choice kung punta ako ng doctor or hospital then sariling bayad or dadaan lahat ng govt.
parang walang aasahan sa govt kung sila pa aantayin
Last edited by shadow; December 25th, 2020 at 01:41 PM.
pfizer and moderna's vaccines contain instructions on how to make the spike protein
The instructions go into cells and cells make the spike and the immune system sees the spike and reacts
Ung bakuna ng sinovac and sinopharm old fashioned vaccines they contain inactivated whole virus
Diba private sector companies bibili ng bakuna ng azn/oxford
Pwede yata mag import as long as approved na ng PH FDA ung bakuna