The coronavirus variant driving India’s devastating Covid-19 second wave is the most infectious to emerge so far. Doctors now want to know if it’s also more severe.
Hearing impairment, severe gastric upsets and blood clots leading to gangrene, symptoms not typically seen in Covid patients, have been linked by doctors in India to the so-called delta variant. In England and Scotland, early evidence suggests the strain -- which is also now dominant there -- carries a higher risk of hospitalization.
Delta, also known as B.1.617.2, has spread to more than 60 countries over the past six months and triggered travel curbs from Australia to the U.S. A spike in infections, fueled by the variant, has forced U.K. to reconsider its plans for reopening later this month, with a local report saying it may be pushed back by two weeks. Singapore found that the mutation accounted for 95% of the local Covid samples linked to variants of concern. Higher rates of transmission and a reduction in the effectiveness of vaccines have made understanding the strain’s effects especially critical.
Stomach pain, nausea, vomiting, loss of appetite, hearing loss and joint pain are among the ailments Covid patients are experiencing, according to six doctors treating patients across India. The beta and gamma variants -- first detected in South Africa and Brazil respectively -- have shown little or no evidence of triggering unusual clinical signs, according to a study by researchers from the University of New South Wales last month.
Some patients develop micro thrombi, or small blood clots, so severe that they led affected tissue to die and develop gangrene, said Ganesh Manudhane, a Mumbai cardiologist, who has treated eight patients for thrombotic complications at the Seven Hills Hospital during the past two months. Two required amputations of fingers or a foot.
“I saw three-to-four cases the whole of last year, and now it’s one patient a week,” Manudhane said.
Doctors are also finding instances of clots forming in blood vessels that supply the intestines, causing patients to experience stomach pain -- their only symptom, local media have reported.
Even as India’s outbreak begins to ease -- daily infections have slipped to less than a quarter of the May 7 peak -- the delta variant is sparking outbreaks elsewhere, including hitherto virus havens such as Taiwan, Singapore and Vietnam, bolstering calls for mass immunization.