China Corona Virus Outbreak

[_Cathy_]

My cousin dropped by at my house today, lahat daw sila (at least in their department) sa SLMC BGC sinovac. He showed me a test yung neutralizing something done at SLMC, nakalagay din reactive. Test was done one month after the 2nd dose ata.

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[boybi]

My cousin dropped by at my house today, lahat daw sila (at least in their department) sa SLMC BGC sinovac. He showed me a test yung neutralizing something done at SLMC, nakalagay din reactive. Test was done one month after the 2nd dose ata.

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Naku Cathy, they might be carriers of covid and they don't know it since they're vaccinated already. Did you let them in your house?

[shadow]

My cousin dropped by at my house today, lahat daw sila (at least in their department) sa SLMC BGC sinovac. He showed me a test yung neutralizing something done at SLMC, nakalagay din reactive. Test was done one month after the 2nd dose ata.

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Ano yun value? Mataas sa cut-off?


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[uls]

Monseratto's post

red circle mine

Notice something sa receptor binding domain (RBD)?

there's no N501Y mutation (the very famous Nelly)

there's only E484K (the notorious Eek)

there are 2 mutations sa N terminal domain (NTD)



significant yun kasi NTD is also a target for antibodies

ung D614G matagal na yan last year pa

[shadow]

Monseratto's post

red circle mine

Notice something sa receptor binding domain (RBD)?

there's no N501Y mutation (the very famous Nelly)

there's only E484K (the notorious Eek)

there are 2 mutations sa N terminal domain (NTD)



significant yun kasi NTD is also a target for antibodies

ung D614G matagal na yan last year pa

Ano nga ibig sabihin? Uubra ba sinovac?


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[bloowolf]

Yes sir.

base sa nababasa ko dito, hind nga clear ang messaging

Don’t take it literally. Term lang yung immunity. The virus is there & is very contagious.
Currently, it affects everyone because we still have no antibodies against it. We have no natural immunity so a lot of people die from it. But there are some who survive & develop an immunity while there are some whose immunity is strong enough to hold off developing the disease? The goal is to make everyone strong enough to be resistant to the disease.
While the virusis is around & will forever be around, it will not get a chance to kill anyone anymore because our bodies are already primed against it should it enter.
Now, no one is built the same. Some are stronger than other unfortunately, with other diseases (comorbs) that makes the defenses weaker so the virus has a better chance of winning.
Our bodies are bombarded with thousands of different infectious agents daily & are good enough to hold off almost all of it.
I wish it were that simple, to defend against this killer but, it is not. So the challenge now is to find the most effective way(s). Which why these vaccines are being developed.
These things are very complicated & very hard to explain. Even regular doctors, unless they are infectious disease experts or molecular microbiologists, will have a hard time explaining it in detail.


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[uls]

scientists focus on the spike gene (S) coz that's the part of the virus that attaches to our cells

and that's what vaccine makers use -- all the Western vaccines present the spike to our immune system and make antibodies that attach to the spike



lahat ng mga vaccines used original Wuhan variant spike

changes to the spike can make new variants less recognizable or barely recognizable to antibodies

[uls]

Ano nga ibig sabihin? Uubra ba sinovac?


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hindi naman... di ko alam... and nobody really knows

unless meron talaga gumawa ng study

theoretical lang naman

[shadow]

hindi naman... di ko alam... and nobody really knows

unless meron talaga gumawa ng study

theoretical lang naman

Pero dapat uubra dahil inactivated virus diba, whole virus ginamit?

Kahit mag mutate ibang part since buong virus kilala ng katawan natin, makikilala pa rin?


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[bloowolf]

Pero dapat uubra dahil inactivated virus diba, whole virus ginamit?

Kahit mag mutate ibang part since buong virus kilala ng katawan natin, makikilala pa rin?


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Ang viruses magagaling, kaya nga hindi natin matalo-talo yan. Wala pa ngang cure sa common cold. Mabilis sila mag adjust. Para syang yung lolo ko na maraming babaeng inasawa at inanakan. Dugo sila ng lolo ko pero hindi namin mahahalata unless kilatisin yung features nila. Kung hindi, makakalusot pa rin at hindi namin malalaman. Parang sila yung variants kung virus sila, haha!


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[_Cathy_]

Naku Cathy, they might be carriers of covid and they don't know it since they're vaccinated already. Did you let them in your house?

No nga HAHAHA. Inunahan ko na, when he asked if he could drop by, sabi ko hanggang garden lang :P I feel bad nga because I could not serve him food or drinks (pero pauwi I sent cookies naman) Nakita nga niya may dumating na delivery and I sprayed everything with alcohol, tapos dun sa receiving area ko may mga nakabilad sa araw and he made a comment na sobrang delikado ko daw LOL

Ano yun value? Mataas sa cut-off?

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oo mataas sa cutoff

[shadow]

No nga HAHAHA. Inunahan ko na, when he asked if he could drop by, sabi ko hanggang garden lang :P I feel bad nga because I could not serve him food or drinks (pero pauwi I sent cookies naman) Nakita nga niya may dumating na delivery and I sprayed everything with alcohol, tapos dun sa receiving area ko may mga nakabilad sa araw and he made a comment na sobrang delikado ko daw LOL



oo mataas sa cutoff

Ano nga!? [emoji36] screenshot mo na lang. [emoji23]


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[uls]

Pero dapat uubra dahil inactivated virus diba, whole virus ginamit?

Kahit mag mutate ibang part since buong virus kilala ng katawan natin, makikilala pa rin?


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in theory yes

-

after you get sinovac, ang antibodies mo more or less tulad ng antibodies ng mga nag recover sa covid

ung antibodies found in convalescent plasma

[carxynogen]

in theory yes

-

after you get sinovac, ang antibodies mo more or less tulad ng antibodies ng mga nag recover sa covid

ung antibodies found in convalescent plasma

Meaning ba nito, yung mga nagka recover sa COVID, no need sinovac since may antibodies na sila?

Pwera na lang cgro if false positive result ng RT-PCR.

[Ry_Tower]

Wala kasing clear messaging from DOH.

The term herd immunity shouldn't be used in this pandemic anymore. Maybe a more apt term like covid mitigation.

As usual, yung dapat sana nagpapaliwanag eh kurapsyon inaatupag kasi. Ano ba bagong relo ni Duque?

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[bloowolf]

Meaning ba nito, yung mga nagka recover sa COVID, no need sinovac since may antibodies na sila?

Pwera na lang cgro if false positive result ng RT-PCR.

Alam mo, sabi ng DOH, pwede na raw pabakuna yung recovered. Pera may neutralizing antibodies pa sila for 6 months. Conflicting.
DOH are policy makers unfortunately.


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[baludoy]

Lahat na ba dito na consistent mag comment naturukan na?

Nakapag engage na ba kayo uli sa rigorous exercises? Ako kasi hindi pa eh (after a week) . Medyo cautious pa din baka biglang may lumabas na blood clot o hemorrhaging, paktay na. [emoji23] lumalaki nanaman tuloy tyan ko [emoji34]

Ginagawa ko planking pa lang at pull-ups. Puro pa alalay . [emoji16]

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[uls]

Meaning ba nito, yung mga nagka recover sa COVID, no need sinovac since may antibodies na sila?

Pwera na lang cgro if false positive result ng RT-PCR.

well... people who recovered from covid have antibodies so maari protective yan

but those antibodies fade

antibodies generated by vaccines should last longer than antibodies generated by natural infection

-

kung duda sa pcr test... like may mga tao nagkaroon ng sintomas ng covid pero nag negative sa pcr

baka noong nagpa-swab sila lumampas na sa time frame when the virus was present in the nasopharyngeal area

to find out if you got covid in the past get an antibody test

[shadow]

Lahat na ba dito na consistent mag comment naturukan na?

Nakapag engage na ba kayo uli sa rigorous exercises? Ako kasi hindi pa eh (after a week) . Medyo cautious pa din baka biglang may lumabas na blood clot o hemorrhaging, paktay na. [emoji23] lumalaki nanaman tuloy tyan ko [emoji34]

Ginagawa ko planking pa lang at pull-ups. Puro pa alalay . [emoji16]

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Ako next day nag jogging na, wala naman akong naramdaman side effects. Sabi dapat daw wala ilan days before and after but why stopped doing yun usual na ginagawa kung wala ka naman naramdaman.

Nagapaolusot ka lang mag exercise. [emoji23]
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[uls]

this is pretty consistent with inactivated virus vaccines

ung efficacy level

can't compare with mRNA vaccines