Moved holes suggest a redesigned logic board, and a redesigned logic board means either new hardware or altered specifications. As a result, even from these small images, it's possible to hazard a guess as to what the iPhone 5S will bring: a more powerful, likely quad-core, processor with 2GB of RAM, possible near-field communications (NFC) capability to better compete with rival Android devices, and the likelihood of increased storage capacity.
Remaining the same, however, will be the retina-class display, which won't see a revision until the true iPhone 6 launches towards the end of next year or the start of 2014.