I'm using 2 printers with CISS installed and on a personal note (psychological as well) I prefer seeing the ink really drain down as compared to refills - na parang orig din na di mo talaga masabi kung ubos na or yung chip lang ang nagsasabing ubos na.
In the long run oks din. I can never tell when I'll print heavily pero at least when that happens, I'm pretty confident that I know I still have plenty.
CISS is good din pala considering pwede ka magpalagay ng external waste tank. Pag refills and napuno na ang waste tank mo kailangan na magpalit, while sa CISS reset lang yung sensors and oks na.
And of course this is for Epson. Not pretty sure with Canon and HP. Just my .02