The most practical would likely be the CR-V. Good drive, comfort, and fuel economy isn't horrible (not this time around). But of the three, my heart definitely goes to the Santa Fe... errh... the Outlander. About the only thing I don't like about its interior is the strange door handle placement (sitting in a huge piece of plastic on the door), but then, it's more posh-looking than the cheap silver on the CRV's door handles.

The Outlander has a great looking and feeling interior. The CRV comes close, and I like the CRV's front seats and color better (personal preference lang yun, though). The Fortuner's interior feels kinda cheap, and the construction of the seats is kinda poor (though they're well padded).

All three handle decently (surprising, for the CRV... didn't really like the handling on the old ones), but the Outlander is sportiest.

Speed? No contest... V6 > I4 > D4D