I guess that would still be on a model to model basis. For old Benzes, the column shifter is a bit more complex as it is a direct mechanical linkage to the transmission living under the center console.

A lot of A/T shifters nowadays are nothing more than electric switches connected by wire to the transmission (even the transfer case lever of the GEN III Pajero is like this). You can practically place them anywhere (even in the stupidest of places like the ceiling, luggage compartment, etc.) and you'd only need longer wires and a way to mount it.