Colgate Total Ingredient Linked to Cancer

[Monseratto]

Use at your risk to your health...

Colgate Total Ingredient Linked to Hormones, Cancer Spotlights FDA Process - Bloomberg

Colgate Total Ingredient Linked to Hormones, Cancer Spotlights FDA Process
By Tiffany Kary Aug 12, 2014 3:12 AM GMT+0800

The chemical triclosan has been linked to cancer-cell growth and disrupted development in animals. Regulators are reviewing whether it’s safe to put in soap, cutting boards and toys. Consumer companies are phasing it out. Minnesota voted in May to ban it in many products.

At the same time, millions of Americans are putting it in their mouths every day, by way of a top-selling toothpaste that uses the antibacterial chemical to head off gum disease -- Colgate-Palmolive Co.’s Total.

Colgate’s Total application included 35 pages summarizing toxicology studies on triclosan, which the FDA withheld from view. The agency released the pages earlier this year in response to a lawsuit over a Freedom of Information Act request. Later, following inquiries from Bloomberg News, the FDA put the pages on its website.

The pages show how even with one of the U.S.’s most stringent regulatory processes -- FDA approval of a new drug -- the government relies on company-backed science to show products are safe and effective. The recently released pages, taken alongside new research on triclosan, raise questions about whether the agency did appropriate due diligence in approving Total 17 years ago, and whether its approval should stand in light of new research, said three scientists who reviewed the pages at Bloomberg News’s request.

Rodent Bones

Among the pages were studies showing fetal bone malformations in mice and rats. Colgate said the findings weren’t relevant. Viewed through the prism of today’s science, such malformations look more like a signal that triclosan is disrupting the endocrine system and throwing off hormonal functioning, according to the three scientists.

Colgate’s application materials also show that the FDA asked questions about the thoroughness of cancer studies, which are partly addressed in recently released documents.

Some questions about triclosan’s potential impact on people are, by nature, unanswerable. Humans are exposed to dozens of chemicals that may interact in the body, making it almost impossible to link one substance to one disease, said Thomas Zoeller, a biology professor at the University of Massachusetts Amherst, who specializes in how chemicals affect the endocrine system.

‘Huge Risk’

“We have created a system where we are testing these chemicals out on the human population. I love the idea they are all safe,” Zoeller said. “But when we have studies on animals that suggest otherwise, I think we’re taking a huge risk.”

New York-based Colgate isn’t accused of wrongdoing, and the 35 pages don’t prove triclosan is harmful. It was the FDA’s decision to keep the documents off of its website, Colgate said.

The FDA followed standard procedure by redacting information that had come from a third party, said spokeswoman Andrea Fischer. Some studies were done in the labs of Ciba-Geigy, the first triclosan maker and a predecessor to its current primary maker, BASF SE, according to the documents. The pages didn’t denote which studies were done by an outside party, or who the party was. Fischer declined to identify them.

Regular Exposure

Zoeller, the endocrine specialist, said that while an estimated 800 to 1,000 chemicals are believed to disrupt the endocrine system, triclosan is one of about 10 to which people are regularly exposed. “We may not have to change very much to have a big impact,” he said.

Total, the No. 3 selling brand in the U.S., lost 2 percent of its market share last year, with $189.8 million in sales for the year that ended on Jan. 26, according to market research firm Mintel Group Ltd. Colgate’s Tom’s of Maine line grew 14 percent, to $38.9 million, suggesting shoppers are gravitating toward more natural options, the report said.

Procter & Gamble, which makes Crest 3D White and Crest Pro-Health -- the top two U.S. toothpastes according to Mintel -- has sought to capitalize. A Google search for “triclosan” and “toothpaste” brings up an advertisement linked to a Procter & Gamble site touting Crest products as “100% triclosan free.”

EU Ban

In 2010, the European Union banned triclosan in materials that come into contact with food. Three years later, the EPA, which reviewed the chemical in 2008, began another review, 10 years earlier than planned. It cited the “rapidly developing scientific database” on the chemical, which includes studies on thyroid effects, according to its website.

Amid these debates, the Natural Resources Defense Council turned its attention to one of triclosan’s main regulators. In 2013, it sued the FDA for the toxicology data the agency had relied on in approving Colgate Total. In January, the FDA handed the NRDC the 35 pages and later put them online along with a previously unreleased cancer study and other information.

The pages included a summary of a 1992 study showing that pregnant mice receiving higher doses of triclosan had lower-weight fetuses and increased incidence of irregular bone formation in their skulls and paw bones. Five of the 120 mice delivered prematurely. A study on pregnant rats the same year found that at higher doses, rat litters had increased incidence of delayed bone formation in areas including the skull, vertebrae and pelvis.

The application dismissed both results -- saying the premature births weren’t dose related and were therefore “incidental.” The bone-formation issues were due to toxic effects on the mother, not the fetus, the summary said.

[uls]

triclosan is used in antibacterial soap

[JohnM]

and foot powder

[shadow]

People nowadays are wuss! Cancerous that, lead this.... Pati mga bata mga pussy dami namamatay sa Watusi eh dati naman boxes and boxes pa kung ibili tayo ng watusi wala naman akong namatay na mga kababata


Sent from my iPad using Tsikot Car Forums

#retzing

[chua_riwap]

How about the other toothpastes in the market?

Ano pwede subst. sa colgate? Baka lahat may triclosan.

[Manilablock]

all natural na lang, ung maliit na branches ng bayabas, kagat kagatin lang ung dulo para mag mukhang brush at un ang ikaskas sa ipin.

[yebo]

EcoWaste Coalition: EcoWaste Coalition Backs Senate Inquiry on Antimicrobial Chemicals

Based on the EcoWaste Coalition’s market survey, some of the products being sold in local retail shops that contain triclosan, triclocarban or trichlorocarbanilide, as shown in the labels, include the following:

BATH SOAP/WASH: Bioderm Whitening Germicidal Soap, Dial for Men Soap, Green Cross Germ Protection Soap, Jergen's Anti-Bacterial Liquid Soap, Maxi Peel Exfoliant Soap, Personal Care Anti-Bacterial Soap, Pure Aid Anti-Bacterial Deodorant Soap, Pure Aid White Anti-Bacterial Beauty Soap, Pure Spring Soap, Safeguard Soap, Vaseline 2 in 1 Healthy Body Wash and Vaseline 2 in 1 Healthy Skin Soap.

HAND SOAP/WASH: Body Treats Anti-Bacterial Hand Soap, Med Guard Anti-Bacterial Hand Soap, Protect and Clean Anti-Bacterial Handwash, Sure Buy Anti-Bacterial Hand Soap and Watsons Anti-Bacterial Moisturizers Hand Soap.

TOOTHPASTE: Colgate Total Professional Clean Toothpaste, Colgate Total Professional Sensitive Toothpaste, Colgate Total Whitening Toothpaste, Hapee Gumtect Advance Toothpaste, Hapee Gumtect Gold Toothpaste, Hapee Compete Toothpaste plus Whitening, Hapee Night Mint Tooth Paste plus Whitening, and Unique Gel Toothpaste.

[chookchakchenes]

Year 2006 non-fluoride toothpaste na gamit ko.

Sa healthy options ako bili either nature's gate or jason's organics.

May allergy ako sa sodium lauryl sulfate. Ayoko din gumamit ng fluoride.

[falken]

EcoWaste Coalition: EcoWaste Coalition Backs Senate Inquiry on Antimicrobial Chemicals

Based on the EcoWaste Coalition’s market survey, some of the products being sold in local retail shops that contain triclosan, triclocarban or trichlorocarbanilide, as shown in the labels, include the following:

BATH SOAP/WASH: Bioderm Whitening Germicidal Soap, Dial for Men Soap, Green Cross Germ Protection Soap, Jergen's Anti-Bacterial Liquid Soap, Maxi Peel Exfoliant Soap, Personal Care Anti-Bacterial Soap, Pure Aid Anti-Bacterial Deodorant Soap, Pure Aid White Anti-Bacterial Beauty Soap, Pure Spring Soap, Safeguard Soap, Vaseline 2 in 1 Healthy Body Wash and Vaseline 2 in 1 Healthy Skin Soap.

HAND SOAP/WASH: Body Treats Anti-Bacterial Hand Soap, Med Guard Anti-Bacterial Hand Soap, Protect and Clean Anti-Bacterial Handwash, Sure Buy Anti-Bacterial Hand Soap and Watsons Anti-Bacterial Moisturizers Hand Soap.

TOOTHPASTE: Colgate Total Professional Clean Toothpaste, Colgate Total Professional Sensitive Toothpaste, Colgate Total Whitening Toothpaste, Hapee Gumtect Advance Toothpaste, Hapee Gumtect Gold Toothpaste, Hapee Compete Toothpaste plus Whitening, Hapee Night Mint Tooth Paste plus Whitening, and Unique Gel Toothpaste.

Sa Close Up nalang ako.:D

Posted via Tsikot Mobile App

[joemarski]

Sa Close Up nalang ako.:D

Posted via Tsikot Mobile App

Buti na lang Close Up na rin ang ginagamit naming Colgate.

Para kasing silicone 'yang Colgate eh, at saka, minsan nala- laglag kapag ni- sawsaw ko 'yung
toothbrush sa basong may tubig. :bwahaha: