If you're gonna travel and leave say around 3am from Carmona, you might end up at NLEX around after an hr since streets would be free. You can then just take SLEX-EDSA (via Magallanes)-NLEX.

If you are not familiar with EDSA and C5, then don't speed up (you might hit barriers if your driver is sleepy).

I once took Sto. Tomas, Batangas to Cainta in 45 mins, so it's possible to get from Carmona to NLEX in an hour driving leisurely.